LDL Lowering in Statin-Intolerant Patients: Practical Use of Bempedoic Acid
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Bempedoic Acid: Mechanism of Action, Effects and Potential Uses
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@biochemistry_nutrition_medlab on Instagram‎: "🫀🧬Inhibition of atherosclerosis by cholesterol-lowering interventions👉🏻Bempedoic acid & statins ⬇️acetyl-CoA & HMG-CoA production by inhibiting ACLY & HMGCR, respectively,thereby ⬇️cholesterol synthesis.Ezetimibe inhibits intestinal uptake of cholesterol by inhibiting NPC1L1. PCSK9 inhibitors ⬇️LDLR degradation by inhibiting PCSK9 expression/function.Bileacid sequestrants bind to BA in the small intestine,thus preventing BA from being reabsorbed
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