The Pickens County Sheriff’s Office said it is holding a blood drive to help a 14-year-old diagnosed with a rare cancer.

Thornton Wilder’s play became a blockbuster musical, but a production under an upstate tent makes the case for its stand-alone virtues.

Clemson softball is bolstering its roster with four new additions from the transfer portal ahead of the 2025-26 season, head ...

Two other upstate waterways, one in Western New York and one in the Adirondacks, also made the list of the nation's best ...

Water you waiting for? From roadside wonders to hidden gems, these waterfalls showcase Upstate New York's natural beauty.

A Greenville woman is accused of leaving her infant child alone in a bathtub where he drowned. READ MORE: ...

Working with researchers at Cornell University and State University of New York Environmental Science and Forestry, DEC ...

What to know about firework displays taking place in Greenville, Spartanburg and Anderson counties to celebrate the Fourth of ...

Maryellen Sheridan, a pediatric clinical nurse specialist at Upstate Golisano Children’s Hospital, has become president of ...

Two youth baseball coaches have been fired after they were filmed stripping naked and streaking at an upstate New York ...

Wegmans is piloting AI-powered Caper Carts from Instacart as part of a smart cart trial across four Upstate New York locations using two tech providers. Caper Carts allow shoppers to skip checkout ...

Syracuse, N.Y. -- Severe thunderstorms capable of bringing damaging winds and torrential rain could hit Upstate New York this ...