BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

High genetic susceptibility to type 2 diabetes is associated with higher atherosclerotic cardiovascular disease risk and ≤1 h/d of television viewing has substantially lower risk of atherosclerotic ...

BACKGROUND: A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated ...

Sex differences in the risk factors, diagnosis, treatment, and outcomes of patients with cardiovascular disease have been well described; however, the bulk of the literature has focused on heart ...

Lymphedema is an incurable disease associated with lymphatic dysfunction that causes tissue swelling and fibrosis. We investigated whether lymphedema could be attenuated by interfering with uPARAP ...

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Dropsy, described in the 17th century, treated with “cure de dechloruration” (bloodletting, leeching, and lancing) and a predecessor of heart failure (HF), yielded to Harvey’s early descriptions of ...

High-quality mechanistic and clinically relevant science to keep clinicians at the forefront of the latest advancements in the diagnosis and treatment of heart failure ...

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