Deficiency in orexin neuropeptide hormones has been linked to narcolepsy, a sleep disorder. People with narcolepsy are more likely to be obese, but how this occurs is unclear, as they do not eat more ...

The concentration of glucose in the blood of humans continuously changes in response to what they eat and the activities they engage in. While many studies have investigated changes in blood glucose, ...

Researchers at the University of Pennsylvania School of Medicine have discovered that the recently identified neurotransmitter orexin (also known as hypocretin) influences reward processing by ...

Full-year 2026 guidance for LUMRYZ net sales is set at $350 million to $370 million, with Alkermes recording the portion ...

A phase 2 trial of Indivior Pharmaceuticals’ opioid use disorder (OUD) candidate has missed its primary endpoint. Indivior ...

The neurotransmitter orexin regulates motivated behaviors such as arousal and feeding—and is now implicated in behaviors associated with addiction in rats. The release of orexin onto dopamine cells ...

When the orexin neurons in the brain are stimulated, pupils expand, new research in mice shows. Orexin is central to the regulation of pupil size. When the orexin system is switched off, the pupils ...

In a recent review published in the Nutrients Journal, researchers examined the current evidence of the intricate relationship between orexin, rapid eye movement (REM) sleep, and appetite. Study: ...

That lucky friend of yours — the one who barely gains weight when eating the same things you eat, even though your waistline expands — might have a hormone called orexin to thank. A new study shows ...

Centessa is one of several companies working on a new class of drugs to treat narcolepsy, a condition that makes it difficult ...

Elaine Chen covers biotech, co-writes The Readout newsletter, and co-hosts STAT’s weekly biotech podcast, The Readout Loud. You can reach Elaine on Signal at elaineywchen.70. A race to develop a new ...

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American It's often interesting to look over the ...