Diagnostics and research analyses involving samples containing maximum-containment viruses present unique challenges, and inactivation protocols compatible with downstream testing are needed. Our aim ...
Mass spectrometry has evolved into an indispensable analytical tool with ionisation techniques at its core. Over the previous decades, numerous methods – from electrospray ionisation (ESI) and ...
EGFR mutation and copy number, EGFR protein expression and KRAS mutation as predictors of outcome with erlotinib in bronchioloalveolar cell carcinoma (BAC): Results of a prospective phase II trial ...
One of the most widely utilized techniques in mass spectrometry imaging (MSI) is label-free MALDI (Matrix-Assisted Laser Desorption Ionization), which can be coupled to a variety of mass analyzers to ...
MALDI remains a powerful tool for analyzing large biomolecules with minimal fragmentation. In this process, peptides or proteins are co-crystallized with a matrix on a metal plate. A laser pulse ...
View in microscopic of normal human cervix cells and squamous epithelial cells. Human cervix cells under magnification. Credit: C&EN/Shutterstock Scientists have long had the tools to identify the ...
Ten consecutive tissue sections from a single C. elegans nematode, shown as optical images (left stack) and corresponding lipid distribution maps generated by MALDI mass spectrometry imaging (MSI) ...
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