Detroit's 2025 slate will be a grind, with 11 games against teams that made the playoffs last season. The team will play eight home games and nine on the road, and will be battle-tested throughout the year for what it hopes is another postseason run.

Iyer picked the top game for all 32 teams' 2025 schedule and wrote that the Rams' matchups against the Detroit Lions in Week 15, the San Francisco 49ers in Weeks 5 and 10, and Atlanta Falcons in Week 17 will be those respective club's best games of their individual seasons.

The Detroit Lions will reportedly open their 2025 NFL season on the road with a matchup against their NFC North rival, the Green Bay Packers.

The Lions and the Packers both made the playoffs in 2024, and each is considered a strong contender for the NFC North crown in 2025. But recent history has been on the side of Detroit, as the Lions have not only won the division title in back-to-back seasons,