Trypanosoma brucei, the causative agent of sleeping sickness in humans, diverged from the highest eukaryotic lineage several hundred million years ago. Understanding epigenetic regulation in T. brucei ...

Trypanosome parasites transmitted by tsetse flies cause devastating diseases in humans and livestock. Different subspecies infect different hosts: Trypanosoma brucei brucei infects cattle but is ...

Trypanosoma brucei, the causative agent of African sleeping sickness, represents a paradigm of parasite evolution and immune evasion. Its ability to periodically change its variant surface ...

Bloodstream forms of Trypanosoma brucei brucei were grown over baby hamster kidney cells in minimum essential medium with various concentrations of metronidazole (Flagyl) and chloroquine. Both drugs ...

Africa, Latin America, and certain regions of Asia face a heavy burden: diseases transmitted by insects, such as mosquitoes or tsetse flies. These often neglected diseases do not just devastate public ...

This image shows a three-dimensional map of the basic structural unit in the parasite Trypanosoma brucei’s flagellum, with various mechanical and motor proteins labeled. Millions of people worldwide ...

Certain regions of Eastern and Central Africa are affected by East African trypanosomiasis especially Botswana, Tanzania, Zaire, Kenya, Malawi,Zimbabwe, Ethiopia, and Uganda .It is caused by the ...

Trypanosomes are parasites that cause deadly diseases in humans and animals, such as Human African Trypanosomiasis (sleeping sickness), Chagas disease, and Nagana in cattle. According to the World ...

Some forms of the single celled parasites, Trypanosoma brucei and Toxoplasma gondii behave like cancer cells, a new study suggests, potentially leading researchers toward new approaches to treat ...

Human African trypanosomiasis (HAT) is transmitted by tsetse flies and, if untreated, is fatal. Treatment depends on infection stage, and early diagnosis is crucial for effective disease management.

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health sheds light on how the blood-borne parasite that causes African sleeping sickness in humans and related diseases ...