Lactic acidosis represents a challenging metabolic complication in patients with haematological malignancies. Notably, type B lactic acidosis occurs in the absence of hypoxia and is associated with ...

In this paper, [4] the authors studied a community-based cohort of patients with a diagnosis of diabetes mellitus and a postdiagnosis serum creatinine measurement who were receiving care in the ...

Lactate is the end product of the cytosolic metabolism of glucose, and its accumulation in the blood signals an increase in production or a decrease in utilization, or both. The liver is a major site ...

We retrospectively investigated the clinical and histopathologic features of hospitalized patients infected with human immunodeficiency virus who had symptomatic lactic acidosis syndrome at a ...

Medications may cause elevated lactate levels which could potentially lead to hyperlactatemia and lactic acidosis, according to a systematic review published in the journal Pharmacotherapy. To improve ...

HONG KONG — A new Japanese and U.S. collaborative study showing that inhibition of the oxygen sensor prolyl hydroxylase domain-containing protein 2 (PHD2) in the liver enhanced uptake of lactate for ...

A hospital in Thailand created a quick-action dialysis protocol for patients with metformin-associated lactic acidosis, a dangerous reaction to a common diabetes drug. The program sharply reduced ...

Metformin-associated lactic acidosis (MALA) is a rare but serious adverse effect of the diabetes drug metformin in which the body accumulates too much lactic acid. Investigators developed and tested a ...

Respiratory acidosis is your body’s response to having too much carbon dioxide (CO2) in your lungs. The large amount of CO2 makes your body fluids and blood acidic to the point where your blood pH is ...