Researchers at Baylor College of Medicine's Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline or ...

Most genetic testing of cancer cells focuses on individual point mutations, single spots in the genome where a base pair has ...

Single-molecule localization microscopy (SMLM) is used to image biological samples at resolutions below the diffraction limit 1,2. The resolution of SMLM is limited by the density of labeling and ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Chinese scientists have uncovered two major genes responsible for sorghum's double-grain spikelet that dramatically enhance grain number and crop yield. A substantial 35.7-kilobase intrachromosomal ...

Structural variants (SVs) correspond to different types of genomic variants larger than 50 bp. Many findings suggest the use of long-read (LR) rather than short-read (SR) sequencing to improve the ...

Chong’s study, “Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak,” was recently published in Nature Communications. UAB researchers have developed a ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

A substantial chromosomal inversion in the DG1 promoter upregulates its expression. It gives rise to a double-grain spikelet trait remarkably augmenting the grain number and yield in sorghum and ...