In something of an identity crisis, the Los Angeles Rams will be out to lock down a favorable playoff matchup when they host the Arizona Cardinals on Sunday at Inglewood, Calif., in the regular-season finale for both teams.

The Los Angeles Rams suffered through a rare dud last weekend, falling to the Carolina Panthers in a turnover-filled 31-28 loss that ended a six-game winning streak.

The Rams lead the league in scoring but in the last 3 weeks, they've also given up the 3rd-most points in the NFL.

The Cardinals have lost eight games in a row and have become one of the worst teams in football, particularly on offense. The Rams should be able to find a rhythm on the ground and through the air, but the defense will still need to be wary of Arizona's playmakers. Here are five key matchups to watch on Sunday.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Arizona Cardinals and Los Angeles Rams.

Chris Simms explains why he believes the NFC East matchup between Dallas and New York will be a "shootout," while Mike Florio thinks the Giants "emptied their tank" last week with a win over the Las Vegas Raiders.

Here's everything you need to know when the Indianapolis Colts play the Houston Texans Week 18 of the 2025 NFL season.

NFL Week 18 predictions, picks for NFL games this week, including Chiefs-Broncos, Vikings-Lions, Seahawks-Rams, Commanders-Cowboys, Bengals-Steelers.