Learning and memory formation involve long-term potentiation (LTP) of synaptic strength. A fundamental feature of LTP induction in the brain is the need for coincident pre- and postsynaptic activity.

Researchers from the National Institute for Physiological Sciences/the Exploratory Research Center on Life and Living Systems (ExCELLS) in Japan identified a TRPA1 stimulant acts as a novel insect ...

Neurostimulation is the application of precise targeted electrical stimulation on nociceptive pathways. Electric stimulation has a long history in medicine for treating various ailments. Beyond the ...

At the bedside examination, neuropathic pain can been distinguished from spontaneous pain, (i.e., stimulus independent) and provoked pain. [70] Spontaneous pain can have several different qualities.

Researchers at UC Santa Barbara identified a pain pathway in fruit flies that reduces the sensation of pain from heat. The researchers discovered that just a single neuron on each side of the animal’s ...

Persistent pain continues even after the damage is resolved, or in some cases, in the absence of an acute injury in the first place. The difference between this and acute pain, also known as ...

There is a largely arbitrary transition between ‘acute’ and ‘chronic’ pain, with temporal cut-offs after which point acute pain becomes chronic pain. Thus, an understanding of the cellular mechanisms ...

Tsukuba, Japan -Innate fear is an essential emotion for animals to avoid danger in a severe natural environment. Rodents kept in a laboratory also show instinctive fear behavior against the smell of ...

Researchers found that a Transient Receptor Potential (TRP) A1 stimulant, 2-methylthiazoline (2MT), act as a potent insect repellent in Drosophila. 2MT induces aversive behaviors via olfactory, ...