Could coffee help to counteract some of the effects of alcohol on the brain, and potentially limit the risk of addiction? That's what's suggested by a new study of how caffeine interacts with the ...

Please provide your email address to receive an email when new articles are posted on . Structural and functional circuit deficits in the mesolimbic reward pathway contributed to measures of social ...

G protein-gated inwardly rectifying potassium (GIRK) channels are critical regulators of neuronal excitability and can be directly activated by ethanol. Constitutive deletion of the GIRK3 subunit has ...

Social rank regulates methamphetamine-seeking behavior by modulating the mesocortical and mesolimbic dopamine pathways, and winning experiences can remodel these circuits to suppress drug-seeking. In ...

Drug addiction poses a global public health challenge, with limited therapeutic options and modest efficacy. While numerous studies have shown that social status profoundly impacts mental health and ...

Dopamine (DA) signalling in the brain is necessary for feeding behaviour, and alterations in the DA system have been linked to obesity. However, the precise role of DA in the control of food intake ...

Anorexia nervosa is a serious mental disorder that manifests with an intense fear of weight gain and a disturbed body image. This can lead to severe diet restrictions or other behaviors like purging, ...