Scientists at the Pasteur Institute in France say they have developed artificial lymphoid organ-chips that recreate much of the human immune system’s response to booster vaccines. The technology, ...
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Tertiary lymphoid structures (TLS) are ectopic cellular hubs that coordinate immunity within patient tumors. TLS also correlate with improved prognosis and superior response to immunotherapy. While ...
A recent Nature Immunology study explores the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during viral infection. Lymphoid tissues play a vital role in ...
The lymphoid organ-chips are created by embedding peripheral blood mononuclear cells (PBMCs) within an extracellular matrix (ECM), which can then be exposed to viral antigens to mimic the effects of ...
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