A cost-effective copper-catalyzed reaction enables selective modification at the C5 position of the indole ring, a backbone for pharmaceutical compounds. Indoles, which form the backbone of many ...
Plants are undeniably one of nature's most promising sources of new medicines, with monoterpenoid indole alkaloids (MIAs) ...
Scientists have cracked one of chemistry’s toughest challenges with indoles, using copper to unlock a spot once thought too stubborn to change. The discovery could pave the way for easier, cheaper ...
The indole nucleus is a privileged scaffold in natural products, pharmaceuticals and agrochemicals. Its unique electronic structure and reactivity at the C2 and C3 positions have spurred the ...
A cost-effective copper-catalyzed reaction enables selective modification at the C5 position of the indole ring, a backbone for pharmaceutical compounds Indole, a molecule made up of a six-membered ...
A research group at Nagoya University in Japan has successfully developed an ultrafast and simple synthetic method for producing indole derivatives. Their findings are expected to make drug production ...
Prenylated indole alkaloids constitute a diverse family of natural products characterised by the attachment of isoprene units to indole-based scaffolds. These compounds display a remarkable range of ...
Indole, and structures derived from it, are a component of many natural substances, such as the amino acid tryptophan. A new catalytic reaction produces cyclopenta[b]indoles -- frameworks made of ...
Indoles abound in bioactive molecules. They make up the molecular core of the essential amino acid tryptophan, the sleep-inducing supplement melatonin, and the psychedelic compound psilocybin.
Flowering plants need indole: Indole is important for plant defense and for attracting pollinators. Indole biosynthesis occurs via a pseudoenzyme: Although TSB-like is essential for indole formation, ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results