Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries — small blood vessels that regulate the movement of ions, water, and metabolites while maintaining ...

Chronic kidney diseases affect more than 10% of the world’s population, and most cases arise from disorders of the kidney’s filtration barrier, which is located within a million microvascular units ...

In patients with diabetic nephropathy, glomerulopathy is an important renal structural change. The kidney consists of four basic tissue types: vessels, glomeruli, tubules, and interstitium. Each of ...

Initially, the researchers observed the specific expression of ADGRF5 within endothelial cells that line the glomerular capillary wall. In mice with genetic knockout of ADGRF5, the GFB was affected by ...

(Upper panel) Normal podocytes: Ephrin-B1 at slit diaphragm interacts with nephrin via the extracellular site and with Par6 via the cytoplasmic site. (Lower panel) Podocytes stimulated by anti-nephrin ...

The kidneys contain millions of microscopic blood vessels known as peritubular capillaries. These vessels recapture helpful nutrients like glucose and minerals and return them to your bloodstream for ...