B cells are a crucial component of immunity, but their function, especially antibody secretion, has largely been studied in the context of secondary lymphoid organs (SLOs) and systemic immune ...

Immune responses and self-tolerance are critical in maintaining systemic and tissue homeostasis. Autoimmune disease results from uncontrolled immune responses against self-antigens, whereas cancer ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...