A once-promising Colts season that included a 7-1 start, has ended without a postseason berth, sparked by a historic late-season collapse.

The Colts are desperate for a win, but that seems far-fetched considering their injuries and that they're going up against a brick wall of a Jaguars team that just undressed the Broncos. The Indianapolis Colts need a win and help to make the playoffs, and that means they must defeat the Jacksonville Jaguars at Lucas Oil Stadium in Week 17.

Several NFL teams will be watching in earnest when the San Francisco 49ers travel to take on the Indianapolis Colts on Monday night in a game chock full of playoff implications for both conferences to close out Week 16.

The Jacksonville Jaguars and Indianapolis Colts meet Sunday in Week 17 at Lucas Oil Stadium in Indianapolis, Indiana. Kickoff is set for 1 p.m. ET.

The San Francisco 49ers have a big Week 16 Monday Night Football clash against the Colts, and here are bold predictions.

The San Francisco 49ers hit the road in Week 16 for a “Monday Night Football” showdown with veteran gunslinger Philip Rivers and the Indianapolis Colts. The game is scheduled to

Learn which TV channel or how to live stream the NFL Week 16 Indianapolis Colts and San Francisco 49ers game, Monday, Dec. 22.

The Jacksonville Jaguars improved to 12-4 after defeating the Indianapolis Colts 23-17 on the road. Next up for Jax? A shot at the AFC South title.