Scientists used fluorescence microscopy to visualize human ACE2 proteins expressed on mouse cells after incubating the cells with fluorescently labeled SARS-CoV-2 spike protein (green). Left: a view ...
A hunter uses duck decoys while shooting real ducks. A new ACE2 decoy mechanism efficiently neutralizes a variety of Covid-19 variants, including Omicron strains. With the continuous evolution of the ...
In a recent study posted to the bioRxiv* preprint server, researchers assessed the ability of spike (S) proteins from 24 animal or human coronaviruses (CoVs) to utilize angiotensin-converting enzyme 2 ...
In a recent study posted to the bioRxiv* preprint server, researchers performed dSTORM (direct stochastic optical reconstruction microscopy) with several labeling techniques for visualizing and ...
Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...
When the COVID-19 pandemic first started, no effective anti-viral drugs were available to fight the disease. However, in record time, so-called monoclonal antibodies were developed as a lifesaving ...
The infamous spike proteins on the surface of SARS-CoV-2 help it bind to and enter human cells. Because of their important role in spreading infection, these spike proteins are one of the main targets ...
The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.