People with end stage ALS lose the ability to breathe, have limited mobility as muscles become paralyzed, and may no longer be able to speak. Amyotrophic lateral sclerosis (ALS) affects certain nerve ...

Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.

ALS and nerve injury symptoms may feel similar. However, ALS is a progressive condition, and the symptoms people may experience typically worsen over time. In some cases, nerve injuries may trigger ...

Pictured are nuclei of induced pluripotent stem cell (iPSC)-derived motor neurons stained for contrast. The nucleus on the left has been treated with DMSO (control) and appears mostly blue. The ...