Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from September 21, 2025 on ESPN.

Mac Jones made his first start for the San Francisco 49ers on Sunday against the New Orleans Saints, four years after ...

The Seahawks, Rams, and Cardinals can figure out their tie at 2-1, the 49ers sit atop the NFC West in first place ...

Expert recap and game analysis of the San Francisco 49ers vs. New Orleans Saints NFL game from September 14, 2025 on ESPN.

Even without Brock Purdy, the San Francisco 49ers were able to get it done. Quarterback Mac Jones led the way as the 49ers ...

San Francisco 49ers running back Christian McCaffrey entered Sunday's Week 1 matchup against the Seattle Seahawks with 1,347 ...

Getting their second consecutive road win to start the 2025 season was good enough news for the San Francisco 49ers. But even ...

RB Alvin Kamara (41) runs with the ball during the New Orleans Saints game against the San Francisco 49ers for Week 2 of the 2025 NFL season on Sept. 14, 2025 at Caesars Superdome.

RB Alvin Kamara (41) runs with the ball during the New Orleans Saints game against the San Francisco 49ers for Week 2 of the ...

Video of the San Francisco 49ers' 16-15 defeat of the Arizona Cardinals on Sunday won't make it into any "classic games" ...

Catch up on all the NFL action from week three as the Philadelphia Eagles and San Francisco 49ers claim late wins, while the ...

It took all of one game for the decision to re-hire Robert Saleh as defensive coordinator to pay big dividends for the San Francisco 49ers. In a game where interceptions and special teams blunders put ...