The biggest game of the 2025 NFL season is here for the Kansas City Chiefs. They are behind in the AFC West standings, and they have not had much success making

Kansas City Chiefs officially ruled out running back Isiah Pacheco for Week 11 vs. Denver Broncos | @EdEastonJr

Running back Isiah Pacheco appears set to miss the pivotal game with an injury, but wider receiver Xavier Worth.y is expected to play. The status of left tackle Josh Simmons, returning to the team after an absence due to a personal matter, was still question mark as of Friday.

The Kansas City Chiefs will be without running back Isiah Pacecho for Sunday’s key AFC West battle against the Denver Broncos.

On the latest edition of the 1st & Orange Podcast, a preview of everything you need to know about Denver’s division-shaping showdown against Kansas City on Sunday at Empower Field.

Everything you need to know on how to watch Denver Broncos vs Kansas City Chiefs NFL Game - team news, livestream, TV channel, and start time.

During Friday's press conference, Kansas City Chiefs linebacker Drue Tranquill described the competition in the AFC West | @EdEastonJr

The Chiefs-Broncos game will be on CBS (KCTV 5 in Kansas City). In Wichita, it’s on KWCH (Channel 12). The game will also be broadcast on radio via KFNZ (96.5 FM) in the KC area, and KNSS (98.7 FM) in the Wichita area. The Chiefs opened as a 3.5-point favorite. The over/under opened at 44.5.

Patrick Mahomes and the Kansas City Chiefs have earned the respect — and the fear — they've been shown in the 2025 NFL season.